quelques études sur les omega-3
et leurs nombreuses applications

2017

Maternal supplementation with fish oil might have prophylactic potential for long-term prevention of asthma in offspring.

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Higher Omega-3: omega-6 ratio is important for fetal health.

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2016

Supplementation with omega-3 fatty acids in the third trimester of pregnancy reduced the risk of persistent wheeze or asthma and infections of the lower respiratory tract in offspring.

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Omega-3 supplementation during either pregnancy or infancy improves child neurodevelopment.

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2015

Supplementing pregnant women with DHA could lead to significant cost savings.

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DHA may improve transplacental iron homeostasis and therefore may enhance iron transfer and boost neonates iron stores at delivery.

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Supplementation of overweight/obese pregnant women with omega-3 fatty acids for >25 weeks reduced inflammation in maternal adipose and the placental tissue.

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2013

A low omega-3 index in late pregnancy was associated with higher depression score three months postpartum.

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2007

Maternal seafood consumption of more than 340 g per week in pregnancy has beneficial effects on child development (ALSPAC-study).

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2003

Maternal omega-3 supplementation potentially reduces subsequent infant allergy.

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Maternal intake of omega-3 during pregnancy and lactation may be favorable for later mental development of children.

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Supplementation of DHA can contribute in optimizing visual development in infants.

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2002

Lower DHA content in mothers' milk was associated with higher rates of postpartum depression.

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2018

Omega-3 fatty acids might be treatment option for ADHD. There is meta-analytical evidence that omega-3 supplementation monotherapy improves clinical symptoms and cognitive performances in children and adolescents with ADHD, and that these youth have a deficiency in omega-3 levels.

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2016

Omega-3 fatty acids may have small effects on emotional lability (characterized by irritable moods with volatile and changeable emotions) and oppositional behavior in subgroups of children with ADHD.

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Possible association between blood Omega-3 Index and cognition in typically developing adolescents.

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2015

Omega-3 improves parent-rated attention in children with and without ADHD.

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2011

Omega-3 fatty acid supplementation, particularly with higher doses of eicosapentaenoic acid (EPA), was modestly effective in the treatment of ADHD.

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2010

EPA supplementation improves teacher-rated behavior and oppositional symptoms in children with ADHD.

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2017

Omega-3 fatty acids may reduce heart patients’ hospital stay.

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Supplementation with EPA+DHA may be associated with reducing coronary heart disease risk, with a greater benefit observed among higher-risk populations.

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Interesting science advisory update on ‘Fish oil for patients with documented coronary heart disease’

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2016

EPA and DHA can reduce blood pressure.

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2015

Omega-3 fatty acids have the potential to beneficially impact arterial wall remodeling and cardiovascular outcomes by targeting arterial wall stiffening and endothelial dysfunction.

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Omega-3 fatty acids have been shown to be associated with reductions in plasma triglyceride levels of approximately 25%- 34%.

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Omega-3 fatty acids have beneficial effects on circulating triglyceride levels in normolipidemic to borderline hyperlipidemic, otherwise healthy, individuals.

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2007

European and American Cardiac Societies incorporated EPA and DHA into treatment guidelines for myocardial infarction, prevention of cardiovascular disease, treatment of ventricular arrhythmias and prevention of sudden cardiac death.

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2004

The Omega-3 Index was inversely associated with risk for coronary heart disease mortality. An Omega-3 Index of > or = 8% was associated with the greatest cardioprotection, whereas an index of < or = 4% was associated with the least.

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2003

Atherosclerotic plaques readily incorporate omega-3 fatty acids from fish-oil supplementation, inducing changes that can enhance stability of atherosclerotic plaques.

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1999

Treatment with omega-3 fatty acids significantly lowered the risk of cardiovascular death after myocardial infarction (GISSI-Prevenzione trial).

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2017

Omega-3 fatty acids promote amyloid-β clearance from the brain through mediating the function of the glymphatic system.

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2016

Omega-3 fatty acids, especially higher doses EPA, may be beneficial in major depressive disorder. Patients taking antidepressants benefit most.

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2015

Omega-3 fatty acids supplementation may attenuate oxidative stress mechanisms, thereby offering benefits for depression prevention.

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2014

The use of omega-3 fatty acids, EPA rather than DHA, improves depressive symptoms in patients with and without diagnosis of major depressive disorder.

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2012

Omega-3 intake may reduce depressive symptoms in older adults with mild cognitive impairment.

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2009

EPA may be more efficacious than DHA in treating depression.

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2008

Supplementation with 1 gram EPA daily for 8 weeks has equal therapeutic effects in major depressive disorder than 20 mg fluoxetine/day.

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2003

A higher ratio of omega-3 to omega-6 fatty acids in erythrocyte membranes was associated with a lower risk of cognitive decline (EVA-study).

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2017

Omega-3 fatty acids alone or in combination with ɤ-Linolenic Acid (GLA) exerted significant clinical benefits in patients with rheumatoid arthritis.

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2015

Daily supplementation with 1 – 2 g fish oil had significant efficacy to improve knee performance in mild to moderate stages of knee osteoarthritics patients.

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2003

A daily dose of 1.6 gram EPA improves joint symptoms in patients with rheumatoid arthritis.

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2002

Intravenous omega-3 fatty acid administration causes reduction of psoriasis, which may be related to changes in inflammatory eicosanoid generation.

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2015

Omega-3 fatty acids may improve symptoms of dry eyes in contact lens wearers.

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Omega-3 fatty acids may improve symptoms of dry eyes associated with prolonged exposure to computer screens.

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2005

DHA is a major structural lipid of retinal photoreceptors. Omega-3 fatty acids may act in a protective role against ischemia-, light-, oxygen-, inflammatory-, and age-associated pathology of the retina.

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2003

DHA protects retina photoreceptors from oxidative stress.

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2017

Omega-3 fatty acids may be beneficial for neuropathy in type 1 diabetes.

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2016

Fish oil may alleviate muscle soreness experienced after resistance training in young untrained females.

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2015

Omega-3 fatty acid supplementation improves aspects of neuromuscular function and performance in male athletes.

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Omega-3 fatty acids supplementation improves endothelial function and maximal oxygen uptake in endurance-trained athletes.

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2017

Omega-3 fatty acids correlate with gut microbiome diversity in women.

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2015

Omega-3 fatty acid EPA may help commensal bacteria in the human gut.

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